The Single Best Strategy To Use For ceesdekker

The Single Best Strategy To Use For ceesdekker

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Nanotechnology gives An array of alternatives to lead to biology. In this article I'll current examples in which nanofabrication – the opportunity to make confined constructions with Proportions at will – is applied to look at the biophysics of one molecules and cells. I'll existing some illustrations from our lab:

Human Rad51 filaments on double- and single-stranded DNA: correlating frequent and irregular types with recombination function.

‘It had been basically a make a difference of picking up a reserve on mobile biology and starting to browse. I'd come from a world of extremely-significant vacuums, cryostats and quantum phenomena, and now I had been Operating at area temperature with molecular biology kits.

Nanofabrication of electrodes with sub-5 nm spacing for transportation experiments on single molecules and steel clusters

Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond smart style in 2005. (nl)

The coiled-coil in the human Rad50 DNA repair protein has precise segments of improved flexibility

We form germs into forms that deviate from their natural phenotype. Specifically, I'll exhibit our capacity to shape Are living E. coli micro organism into novel designs for instance rectangles, squares, triangles and circles.

2000, discovery that nanotubes can have extraordinary huge recent densities; fixed the controversial problem of Digital transportation by DNA molecules by measurements of insulating behavior at the single molecule stage; and demonstration of the AFM method for one-molecule manipulation of nanotubes

This "Cited by" rely includes citations to the following content articles in Scholar. Those marked * can be different in the write-up while in the profile.

At the moment, we also recognized that it should be feasible to make use of just one semiconducting carbon nanotube to create a transistor — and we set out to really make it. We stretched unique semiconducting nanotubes throughout metallic electrodes and utilised the underlying silicon substrate like a gate electrode, establishing the basic three-terminal layout of the subject-result transistor (Fig.

Illustration (4) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is revealed in gray, the rim with the pore is highlighted in purple, as well as a 3D rendering in the motion of your DNA rod is shown.

2001, discovery of single-electron transistors at place temperature based upon nanotubes; realization of to start with logic circuits with carbon nanotube equipment; and discovery of the molecular structure of DNA repair enzymes with AFM

Visualization of unstained DNA nanostructures with State-of-the-art cees dekker in-focus transmission electron microscopy methods

Solid-state nanopores have proven to become a remarkably flexible probe for single-molecule Evaluation of DNA. I will describe some of our recent conclusions – precisely DNA knots – and our endeavours to expand the abilities of good-point out nanopores even even further, from the route of solitary-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.